Clinicians call for greater awareness of how hormone fluctuations contribute to anxiety, depression, brain fog, and mood instability during perimenopause and menopause BURLINGAME, CALIFORNIA – (July 24, 2025): As the population of middle-aged adults (ages 40–65) continues to grow in the U.S., so too does the need to better understand the unique mental and physical health challenges of this demographic. While conversations around midlife wellness often focus on burnout, family stress, or sleep deprivation, emerging clinical evidence highlights a lesser-known driver of mental distress: hormone changes. Experts at JumpstartMD are calling attention to the critical role of hormonal shifts during perimenopause and menopause and their underappreciated impact on emotional resilience, cognition,…